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KMID : 0388420010110010067
Konkuk Journal of Medical Sciences
2001 Volume.11 No. 1 p.67 ~ p.76
Clinical Observations of Acute Myocardial Infarction in ChoongJu Area over 10 years of Period
Park Bong-An

Ryu Ha-Kun
Lee Jong-Hyuk
Kim In-Sook
Ryu Ju-Sung
Yu Jae-Deung
Lee Yong-Gu
Moon Eon-Soo
Kim Hyeong-Su
Abstract
Background: The current treatments of acute myocardial infarct(AMI) include noninvasive method using thrombolytics and invasive methods such as primary percutaneous transluminal coronary angioplasty(PTCA) and coronary artery bypass graft (CABG) surgery. Although there are many studies comparing the effectiveness of noninvasive and invasive methods, when large clinical centers. 20% of total hospitals, were excluded, most middle-sized hospitals lacked personnels and facilities for the invasive methods. Thus they opted for the noninvasive methods. Therefore, in this study, the clinical characteristics of AMI patients and the results of thrombolytic & conservative treatment were observed.

Method: 137 patients with acute myocardial infarct, who visited KonKuk University Medical Center, ChoongJu Hospital during Sept. 1990 to Sept. 1999 were analysed retrospectively using medical records.

Result: The sexual compositions of patients were 63.5% male, and 36.5% female. The mean age for male patients were 56¡¾12.9, and for female patients 68.7¡¾9.6(p<0.05). The mean age for female patients was significantly older than male patients. The patients in the thrombolytic treatment group had mortality rate of 6.25% which is lower than that of the conservative treatment group at 12%(p>0.05).

Conclusion: Although in ours study, small number of acute myocardial infarct patients caused the statistical insignificance, rapid revascularization by thrombolytic therapy within 6 hours of onset of symptoms improved mortality rate and early ambulation. And we had good results on AMI with thrombolytic agent in ChungJu including near rural area as primary emergency hospital. Therefore a prospective research with greater number of subjects is needed to develop better treatments for AMI.
KEYWORD
AMI, thrombolytic therapy, PTCA, CABG
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